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Our research aims to understand the processes that ‘make and shape’ organs during animal development

We are interested in how organ form and function emerge during development. The types of question we ask include: how are organ size and shape controlled; how are cell and tissue polarity established; what makes cells become different and adopt specialised functions; and, how do these functions integrate to produce the emergent properties of the organ. We focus on simple organs in Drosophila, which have the advantage of being easy to manipulate experimentally yet share many features with the more complex organs found in vertebrates. Our goal is to reveal fundamental aspects of organogenesis and apply this knowledge to help us understand the organs of our own body, and to learn something about what goes wrong during disease.

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